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What killed my cat? He was given multiple shots month after month for 6 months. My cat hasn't been eating lately, so my vet prescribed mirtazapine as an appetite stimulant. No so. The use of mirtazapine as an appetite stimulant in cats has been discussed previously in this Forum, but remains an important topic due to its widespread use in feline medicine. It did make both of them pretty vocal. Mirtazapine is an antidepressant when used in people, and it turns out that this drug also possesses appetite-stimulating properties. I didn't know about its potential to induce serotonin syndrome so I was quite shocked when I checked her symptoms against mirtazapine side effects online. He lost 4 lbs. They each only had 1/4-1/8 pill every 3-4 days a couple of times (at different times) and then their appetites came back. A commonly prescribed anti-seizure medication, phenobarbital makes the body produce more CYP enzymes, which increases the clearance and decreases the effectiveness of many types of medications, including digoxin, glucocorticoids, amitriptyline, clomipramine, theophylline, and lidocaine. Not long after I gave her her first pill, she was acting really hungry, so I filled up her plate and she ate all of it, something she hasn't done in years. On the label, it says "May cause vocalization or odd behavior." (She had reacted two weeks ago to a shot of Convenia, having extreme lethargy … Vet gave me Mirtazapine instead of Cypro for my 17yr old with IBD & now CRF. My cat was given 1/4 tab of Mirtazapine yesterday around 2:30 pm, along with 150ml of subQ fluids, as she was dehydrated. This effect has been observed in dogs but not in cats. I've used mirtazapine for both my cats, one has kidney disease and one has IBD. Anyway I gave him 1/4 of the … in 1 month. Now my one cat who is just over 1 is a deterrent My cat, Saoirse, only ever received one dose of mirtazapine and her pupils were like dinner plates plus she had other quite alarming side effects. The problem with oral use in the cat is that the human 15mg tablet cannot easily be cut smaller than into quarters. He had a large round hole in his stomach. It is a business. Oral Use in Cats The tablet form can also be used in cats but is given every 1, 2 or 3 days. And someone, somewhere then had an “Ah Ha moment” wondering if the drug would work as an appetite stimulant in cats, and to be delivered as a transdermal rather than a pill. I gave her three servings and she licked the plate clean and went to her bed. If mirtazapine does not seem effective for a dog, consider a different product such as capromorelin or cyproheptadine. Sadly enough, I believed in the vets treating him that they had his best interest at heart. The U.S. Food and Drug Administration (FDA) recently approved Mirataz (mirtazapine transdermal ointment), a new animal drug used to manage undesired weight loss in cats. by Kim (FL) To make a long story short, he was let outside and found the next day, disemboweled with no blood. My Vet recommended the same as an appetite enhancer and it had a complete opposite effect. Gave him some this am about 4 hours ago and now he is restless and calling. He keeps going to the food dish and eating a few bits, sits for a few minutes, wanders around & vocalizing. VetVine is an accredited Continuing Education provider for veterinary professionals and resource of expert-driven pet health information for pet owners. Cerenia killed my cat. My cat at the moment is around 12 lbs lost a lot of weight since he has been sick, normally he is around 16lbs not fat just big. ... My older cat who is indoor-outdoor during the summer months has lived with my other 2 indoor cats for a year. 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